This is the first time the mixed team event is held over 6km - 4x1500m. The previous mixed events at the world aquatics championships were held in 5km or 25km formats.

Germany won the mixed team event at three of the past four world aquatics championships (2013, 2015, 2019). It recorded its worst result in the mixed team event at the previous world championships in Budapest, in 2017 (8th place).

France won the mixed team event at Budapest 2017. Aurélie Muller (FRA) and Marc-Antoine Olivier (FRA) were part of that gold-medal winning team and they could win a record-equalling second gold medal in the mixed team event.

United States (G2-S1-B1) and Germany (G3-S0-B1) have won a record four medals in the mixed team events at the world aquatics championships.

Rachele Bruni (ITA, G0-S1-B1) and Giulia Gabbrielleschi (ITA, G0-S1-B1) could equal the record of winning three medals in mixed team events at the world aquatics championships, set by Isabelle Härle (GER, G2-S0-B1) and Ashley Twichell (USA, G1-S1-B1).